Silver-catalyzed enantioselective functionalizations of alkenes and alkynes: A short review

Transition metal-catalyzed asymmetric transformations of alkenes and alkynes can upgrade readily available unsaturated compounds to valuable building blocks for organic synthesis. Late transition metals supported by ligands, particularly palladium, rhodium, iridium, have traditionally been employed enantioselective functionalization alkynes, but these precious are costly. Silver is a much less expensive late metal with good Lewis acidity that accommodate diverse ligands coordination geometries. Silver(I) complexes also capable engaging in non-covalent interactions drive selectivity reactions at both the bond, as well an adjacent activated allylic or propargylic C–H bond. This short review summarizes recent developments silver-catalyzed alkene-containing alkyne-containing compounds. Direct alkene/alkyne π bond described, examples where site unsaturation drives